What are the factors that affect the treatment of vitiligo?

What are the factors that affect the treatment of vitiligo?

Vitiligo is a refractory skin disease, and its treatment takes a relatively long time. And the clinical treatment effect of vitiligo is very different among individuals. The treatment effect of vitiligo also varies greatly in different periods, different parts, even if it is the same individual. So what are the factors that affect the treatment of vitiligo?

①The size of white patches'area

In the small area of lesions, the melanocytes of normal skin at the margin of white patches can expand to the center of the white patches by creeping proliferation, and connect with the newly emerged pigment islands around white patches, and eventually cover it. While large area of white patches, it can only rely on the activation, proliferation and migration of melanocytes in the follicle bulb in the skin lesions, but eventually form pigment spots only , hard to connect into pieces, Therefore, treatment is much more difficult.

②The length of the disease

In short course of disease, melanocytes have not been completely destroyed and disappeared in white spot area, inactive melanocytes still exist in the hair follicle, which may be recovered by timely treatment, and finally produce melanin. While in long course of the disease, melanin in the white spot is completely destroyed and disappeared. It’s relatively difficult to have the treatment only by the proliferation of inactive melanocytes in hair follicle.

③Different sites of disease

Usually, treatment for white patches on face are the fastest, followed by the head,neck, back, front chest, hands, feet and mucous membranes. The therapeutic effect of different sites varies a lot.

④Individual difference

The vitiligo treatment of teenagers is easier than adults. The older someone is, the more difficult the treatment is, which is related to the nosogenesis and the metabolic state of body. The body function of adolescent is relatively active, the absorption capacity of drugs is better relatively,the

recovery of melanocytes is faster after systemic treatment.Thus, to stop the development of white patches. And then the treatment period shorten, the condition of vitiligo can get improvement and recovery.

⑤Other factors

Other factors that affect the treatment effect of vitiligo include whether patients cooperate with doctors for treatment actively, whether they pay attention to the collocation of diet, whether they maintain a good life and rest, etc, as well as trauma and various environmental factors.

Vitiligo is different from other common skin diseases, the etiology is complex,and there is no special drugs for all the vitiligo patients. As a result, there is a phenomenon, that the same treatment is used, but the effectiveness varies from person to person. Therefore, patients need to fully understand the disease. Early detection, timely treatment.