The Principle of 308 Excimer Laser Treatment for Vitiligo

The U.S. Xtrac 308 excimer laser treatment system is the pinnacle of dermatological laser treatment, which integrates many of the world's top technologies such as the 308nm XeCl excimer laser light source, quasi-continuous nano-modulation at 154Hz, and the latest liquid light source delivery (LLG). This treatment system uses XeCl excimer gas. Clinical research shows that a single 308nm wavelength is the best wavelength for inducing apoptosis of pathological T lymphocytes in vitiligo and psoriasis lesions, and is also the more penetrating wavelength in the UVB band, penetrating up to 1.5mm into the superficial dermis. therefore, it has a good effect on treating vitiligo, psoriasis, and other skin diseases. This principle is utilized in medicine by directly irradiating the skin lesions with laser light to cause relevant biological and chemical changes, thus promoting the synthesis of skin pigment and achieving the purpose of treatment.

The specific principles of excimer laser treatment for skin diseases are:

1. Induce T-cell death and improve local immunity disorder (the direct cause of vitiligo is caused by the T-cells settled in the skin killing the melanocytes in the skin).

2. Stimulate melanocyte proliferation (the skin and hair follicles will remain part of the melanocytes that escaped autoimmune damage, the excimer laser can stimulate the remaining melanocytes to divide and proliferate, prompting the resting melanocytes outside the hair follicle myelin sheath to heterogeneously to the white spot area disease wake up to divide and proliferate and produce melanin).

3. Improve local microcirculation and promote melanocyte synthesis of melanin.

4. Promote vitamin D3 and melanocytes, keratin-forming cell function is closely related.

5. Activate pseudo-peroxidase. The pseudo-peroxidase in the local skin can remove oxygen free radicals and provide a clean-living environment for keratinocyte melanin settled in the skin. The excimer laser can remove the living environment of harmful oxygen free radicals by activating pseudo-peroxidase.