How Vitamin D3 Preparations Treat Vitiligo

Tacalcitol Ointment is a kind of active vitamin D3 preparations, we need to apply this ointment twice a day and observe the treatment effect after one month. Tacalcitol can make the original pigment generate in advance. Pigment regeneration will increase obviously from second months. So for those patients who have a poor treatment effect or slow effect we can combine the tacalcitol ointment and other treatment methods to improve treatment effect that can accelerate the regeneration of pigment. Besides that the tacalcitol ointment can use patients with a sensitive skin lesions part or some adults or children vitiligo patients have adverse effect to the glucocorticoid hormones and psoralen long wave UV therapy.

Tacalcitol ointment combine the NB-UVB irradiation will accelerate the onset time and reduce the course of treatment, decrease the NB-UVB accumulating dosage and adverse effect. We apply the tacalcitol ointment evenly and thinly on the lesion part, after 30 minutes we use the NB-UVB therapy. At beginning the dosage of irradiation amount is 0.5J/cm² for the local part of body, the whole body irradiation amount is 0.4J/cm²， irradiation twice every week, and the irradiation amount increase 0.1J/cm² increase progressively. maintain the original irradiation dosage if there are any slight erythema or itchiness symptoms, or maintain the original irradiation dose until symptoms disappear. If the erthema area is painful or have any blisters, start to irradiat until the lesion part gradually vanish, the irradiation dosage reduce 20%, irradiation amount maximum can attain 3.0J/cm ². Facial and cervical lesion part is most sensitive to the treatment, the treatment effect is best, the trunk effect is next, the hands and foots area the treatment effect is poor, but the side effect is less when combine with other therapies.