Can vitiligo coexist with other skin diseases? The answer is yes. The common skin diseases that coexist with vitiligo are psoriasis, alopecia areata, dermatographism, atrophic leukoplakia, twenty-nail dystrophy, persistent abnormal pigmentation erythema, follicular skin atrophy, and basal cell carcinoma.

Psoriasis is a common clinical skin disease, typically manifesting as a chronic recurrent erythematous scaly skin disease, the cause of which is related to genetic, immune, endocrine, infectious, and psychiatric factors. Clinical research surveys show that: the proportion of psoriasis patients has significantly increased to natural people in recent years, and it is also found that many patients do not have vitiligo lesions at their psoriasis lesions, but some psoriasis lesions often have depigmented patches, and hypopigmented patches often appear between psoriasis lesions and normal skin, which may be related to the fact that melanocytes are more easily damaged in psoriasis patients.

Alopecia areata is also a clinically common condition in which limited hair loss is seen. The etiology is considered to be related to mental stress, endocrine disorders, and autoimmunity. A survey report shows that patients with vitiligo-complicating alopecia areata are four times more likely than those with vitiligo disease alone. Consider the cause may be due to psychoneurological factors through the immune system on melanocytes.

Dermatographism, also known as artificial urticaria, often begins with itching or burning of the skin, and itching or hydrogenation is followed by the appearance of localized thread-like skin lesions, which are positive for skin scratching. The etiology is related to psychological factors, immune reactions, and allergic reactions.

Atrophic leukoplakia, white spot disease. Typical lesions appear as porcelain white flat papules with small blackhead acne-like follicular keratinous plugs surrounded by a red halo. In later stages, sclerosis and atrophy of the skin and mucous membranes with hypopigmented spots may occur. The disease is best found in the genital area of both sexes. Its development is considered to be related to genetics, sex hormone levels, autoimmune abnormalities, and other factors. Some scholars speculate that the complication of the two diseases may be due to the exposure of surface antigens of melanocytes and keratin-forming cells due to metabolic disorders and certain other factors in the process of melanin synthesis and that the two diseases share a common immunopathological mechanism.