Will vitiligo influence the next generation?

Researchers have found that there are 20 to 50 percent of vitiligo patients that their relatives are affected, and about 6 % have siblings with the disease. A study of 2,624 vitiligo patients in North America and the United Kingdom found, the incidence is 6% in siblings of vitiligo patients, and of 23 % in monozygotic twins.

The familial aggregation of vitiligo suggests that the disease has a genetic basis. Genetic studies show that it is a non - Mendelian, multi - factor, multi - gene inheritance pattern. Although there are different reports on the incidence of vitiligo in family members, according to foreign data statistics, the closer the blood relationship, the higher the risk of disease.

There is a genetic factor for vitiligo, but not all individuals will develop the disease. Non-genetic or environmental factors also play a role in the pathogenesis of the disease, such as industrial pollutants, large amount of chemical pesticide residues in agriculture, exposure of the sun, stress of life stress, and trauma. Therefore, offsprings generally develop the disease under both genetic and environmental factors.

Some female patients with vitiligo will be irritable and bored during pregnancy, it will lead to human endocrine disorders when people are in the state of psychological pressure and mental overtension for a long time. Negative emotions can affect the normal development of the fetus, which makes it easier to express the disease genes that the fetus carries. It can cause the baby to get sick, and the pregnant woman can also get sicker herself.