Why Mental Factors can Trigger Vitiligo?

The occurrence of vitiligo is closely related to mental factors. The regulation of neurohumoral prompted the production of melanin, and the central nervous system has a close relationship with the occurrence of vitiligo. In a survey of vitiligo, scholars have found that a certain number of vitiligo patients in the early or stable stage of the disease, when it has improved or even healed if it is again subjected to mental trauma, excessive use of the brain or nervousness and other factors will cause the white spots to expand, increase or relapse.

Local nerve damage can also trigger the occurrence of white spots. The patient's white spots are distributed in bands or strips along the nerve segments or dermatomes, and sometimes the white spots also appear along the corners of the mouth to the jaw angle after herpes zoster, the patient is accompanied by local sensory dullness. It has been reported that vitiligo occurs in areas innervated by injured brachial plexus nerve fibers. It has also been found that segmental vitiligo has nerve fibers reaching into the melanocytes at the junction of the white spots and normal skin, which is not seen in normal skin.

Central nervous system lesions can trigger vitiligo as well. A large amount of information shows that some infectious diseases such as syphilis, leprosy, and pinta disease will not only cause system damage but are also accompanied by changes in skin color. One scholar said that the change of skin color and central nervous system lesions are also related, such as multiple sclerosis patients' skin can also appear in vitiligo-like hypopigmented spots. In segmental vitiligo, the distribution of the lesions is segmental, involving one or several nerve segments, not crossing the midline of the body, with a unilateral distribution.