Why Vitiligo Can be Caused by inflammation?

The inflammatory factors of vitiligo include local inflammation and systemic inflammation, local inflammation includes infection and non-infection types. Various bacteria, viruses and fungi, and pathological exudate formed by degenerated and dead tissue cells can release a variety of antigenic substances, triggering the body's immune response, local inflammatory reaction in the release of a variety of inflammatory mediators, cytokines can damage melanocytes, thus making melanocytes cells induce the production of anti-melanocyte antibodies. In inflammatory skin diseases, the loss of melanocytes due to liquefied degeneration of basal cells causes local cell proliferation, epidermal thickening, and poor contact between melanocytes and keratinocytes, which affects the transmission and degradation of melanosomes, leading to melanosome blockage and stimulation of melanocyte hypofunction or death.

It is worth mentioning that the clinical often see some adolescent facial simple white pity can be further transformed from a secondary hypopigmentation spot to a pigment loss spot, and some initial facial vitiligo is easily misdiagnosed as simple white pity, thus also delaying the treatment. In addition, there are many children with mosquito bites, and scratching resulting in skin inflammation, and can also induce vitiligo.

In clinical experience, some patients would get vitiligo or aggravate it after a cold, fever, or sore throat. There are also some patients who suffer from viral infections such as chickenpox and develop white patches on the lesions and sometimes on the normal skin between the lesions. This is mainly because these inflammatory diseases cause local nerve cell damage in the patient's body or lead to organism stress reactions, triggering local or systemic immune or endocrine dysfunction in the body and eventually inducing vitiligo. In addition, some suffer from eczema, urticaria, and other allergic skin diseases patients, triggering vitiligo's main cause is the disorder of the immune system.

At present, there are many patients who do not know enough about inflammatory vitiligo and miss the best time for treatment, thus leading to the serious development of the disease. In fact, in daily life as long as you understand inflammatory vitiligo, you can detect as well as treat inflammatory vitiligo earlier, thus reducing the impact of inflammatory vitiligo on us. For vitiligo patients, as long as you find the right hospital, find the right doctor, and receive treatment actively, we believe you will overcome the vitiligo soon.